RMEL3, a novel BRAF(V600E)-associated long noncoding RNA, is required for MAPK and PI3K signaling in melanoma

Previous work identified RMEL3 as a lncRNA with enriched expression in melanoma. Analysis of The Cancer Genome Atlas (TCGA) data confirmed RMEL3 enriched expression in melanoma and demonstrated its association with the presence of BRAF(V600E). RMEL3 siRNA-mediated silencing markedly reduced (95%) co...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Goedert, Lucas, Pereira, Cristiano G., Roszik, Jason, Plaça, Jessica R., Cardoso, Cibele, Chen, Guo, Deng, Wanleng, Yennu-Nanda, Vashisht Gopal, Silva, Wilson A., Davies, Michael A., Espreafico, Enilza M.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095033/
https://ncbi.nlm.nih.gov/pubmed/27167340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9164
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