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Imprime PGG-Mediated Anti-Cancer Immune Activation Requires Immune Complex Formation
Imprime PGG (Imprime), an intravenously-administered, soluble β-glucan, has shown compelling efficacy in multiple phase 2 clinical trials with tumor targeting or anti-angiogenic antibodies. Mechanistically, Imprime acts as pathogen-associated molecular pattern (PAMP) directly activating innate immun...
שמור ב:
| הוצא לאור ב: | PLoS One |
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| Main Authors: | , , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Public Library of Science
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5094785/ https://ncbi.nlm.nih.gov/pubmed/27812183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165909 |
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