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A Phase 2 Efficacy and Safety, Open-label, Multicenter Study of Imprime PGG Injection in Combination with Cetuximab in Patients with Stage IV KRAS-Mutant Colorectal Cancer
BACKGROUND: Imprime PGG is an innate immune cell modulator that primes neutrophils and monocytes/macrophages to exert anti-tumor activity against complement opsonized tumor cells. In patients with KRAS-mutant colorectal cancer (CRC), cetuximab alone is ineffective; however, it can bind to tumor cell...
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Publicado no: | Clin Colorectal Cancer |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5621519/ https://ncbi.nlm.nih.gov/pubmed/26975418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clcc.2016.02.013 |
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