Class III P-glycoproteins mediate the formation of lipoprotein X in the mouse.
Cholestasis is associated with hypercholesterolemia and appearance of the abnormal lipoprotein X (LpX) in plasma. Using mice with a disrupted Mdr2 gene, we tested the hypothesis that LpX originates as a biliary lipid vesicle. Mdr2-deficient mice lack Mdr2 P-glycoprotein, the canalicular translocator...
Na minha lista:
| Publicado no: | J Clin Invest |
|---|---|
| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1998
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC509123/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9802889/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI3597 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|