Class III P-glycoproteins mediate the formation of lipoprotein X in the mouse.
Cholestasis is associated with hypercholesterolemia and appearance of the abnormal lipoprotein X (LpX) in plasma. Using mice with a disrupted Mdr2 gene, we tested the hypothesis that LpX originates as a biliary lipid vesicle. Mdr2-deficient mice lack Mdr2 P-glycoprotein, the canalicular translocator...
Sábháilte in:
| Foilsithe in: | J Clin Invest |
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| Príomhchruthaitheoirí: | , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe / Cruthaithe: |
American Society for Clinical Investigation
1998
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| Ábhair: | |
| Rochtain ar líne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC509123/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9802889/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI3597 |
| Clibeanna: |
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
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