Class III P-glycoproteins mediate the formation of lipoprotein X in the mouse.

Cholestasis is associated with hypercholesterolemia and appearance of the abnormal lipoprotein X (LpX) in plasma. Using mice with a disrupted Mdr2 gene, we tested the hypothesis that LpX originates as a biliary lipid vesicle. Mdr2-deficient mice lack Mdr2 P-glycoprotein, the canalicular translocator...

Cijeli opis

Bibliografski detalji

Izdano u:	J Clin Invest
Glavni autori:	Elferink, R P, Ottenhoff, R, van Marle, J, Frijters, C M, Smith, A J, Groen, A K
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Clinical Investigation 1998
Teme:	Research Article
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC509123/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9802889/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI3597
Oznake:	Dodaj oznaku Bez oznaka, Budi prvi tko označuje ovaj zapis!