Omeprazole Induces Heme Oxygenase-1 in Fetal Human Pulmonary Microvascular Endothelial Cells via Hydrogen peroxide-Independent Nrf2 Signaling Pathway

Omeprazole (OM) is an aryl hydrocarbon receptor (AhR) agonist and a proton pump inhibitor that is used to treat humans with gastric acid related disorders. Recently, we showed that OM induces NAD (P) H quinone oxidoreductase-1 (NQO1) via nuclear factor erythroid 2–related factor 2 (Nrf2)-dependent m...

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Publicado en:Toxicol Appl Pharmacol
Main Authors: Patel, Ananddeep, Zhang, Shaojie, Shrestha, Amrit Kumar, Maturu, Paramahamsa, Moorthy, Bhagavatula, Shivanna, and Binoy
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5089963/
https://ncbi.nlm.nih.gov/pubmed/27725188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2016.10.002
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