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Omeprazole Induces Heme Oxygenase-1 in Fetal Human Pulmonary Microvascular Endothelial Cells via Hydrogen peroxide-Independent Nrf2 Signaling Pathway
Omeprazole (OM) is an aryl hydrocarbon receptor (AhR) agonist and a proton pump inhibitor that is used to treat humans with gastric acid related disorders. Recently, we showed that OM induces NAD (P) H quinone oxidoreductase-1 (NQO1) via nuclear factor erythroid 2–related factor 2 (Nrf2)-dependent m...
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| Publicado no: | Toxicol Appl Pharmacol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5089963/ https://ncbi.nlm.nih.gov/pubmed/27725188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2016.10.002 |
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