Omeprazole Induces NAD(P)H Quinone Oxidoreductase 1 via Aryl Hydrocarbon Receptor-Independent Mechanisms: Role of the Transcription Factor Nuclear Factor Erythroid 2–Related Factor 2

Activation of the aryl hydrocarbon receptor (AhR) transcriptionally induces phase I (cytochrome P450 (CYP) 1A1) and phase II (NAD(P)H quinone oxidoreductase 1 (NQO1) detoxifying enzymes. The effects of the classical and nonclassical AhR ligands on phase I and II enzymes are well studied in human hep...

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Vydáno v:Biochem Biophys Res Commun
Hlavní autoři: Zhang, Shaojie, Patel, Ananddeep, Moorthy, Bhagavatula, Shivanna, Binoy
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618076/
https://ncbi.nlm.nih.gov/pubmed/26441083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.09.173
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