Leflunomide Induces NAD(P)H Quinone Dehydrogenase 1 Enzyme via the Aryl hydrocarbon Receptor in Neonatal Mice

Aryl hydrocarbon receptor (AhR) has been increasingly recognized to play a crucial role in normal physiological homeostasis. Additionally, disrupted AhR signaling leads to several pathological states in the lung and liver. AhR activation transcriptionally induces detoxifying enzymes such as cytochro...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Shrestha, Amrit Kumar, Patel, Ananddeep, Menon, Renuka T., Jiang, Weiwu, Wang, Lihua, Moorthy, Bhagavatula, Shivanna, Binoy
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367632/
https://ncbi.nlm.nih.gov/pubmed/28192119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.02.051
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