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Oncolytic Adenoviruses Targeted to Human Papilloma Virus-Positive Head and Neck Squamous Cell Carcinomas

OBJECTIVES: In recent years, the incidence of Human Papilloma Virus (HPV)-positive head and neck squamous cell carcinomas (HNSCC) has markedly increased. Our aim was to design a novel therapeutic agent through the use of conditionally replicative adenoviruses (CRAds) that are targeted to the HPV E6...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oral Oncol
Hauptverfasser: LaRocca, Christopher J., Han, Joohee, Oliveira, Amanda R., Davydova, Julia, Herzberg, Mark, Gopalakrishnan, Rajaram, Yamamoto, Masato
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5089835/
https://ncbi.nlm.nih.gov/pubmed/27086483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2016.02.014
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