Length of Variable Numbers of Tandem Repeats in the Carboxyl Ester Lipase (CEL) Gene May Confer Susceptibility to Alcoholic Liver Cirrhosis but Not Alcoholic Chronic Pancreatitis

BACKGROUND: Carboxyl-ester lipase (CEL) contributes to fatty acid ethyl ester metabolism, which is implicated in alcoholic pancreatitis. The CEL gene harbours a variable number of tandem repeats (VNTR) region in exon 11. Variation in this VNTR has been linked to monogenic pancreatic disease, while c...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Fjeld, Karianne, Beer, Sebastian, Johnstone, Marianne, Zimmer, Constantin, Mössner, Joachim, Ruffert, Claudia, Krehan, Mario, Zapf, Christian, Njølstad, Pål Rasmus, Johansson, Stefan, Bugert, Peter, Miyajima, Fabio, Liloglou, Triantafillos, Brown, Laura J., Winn, Simon A., Davies, Kelly, Latawiec, Diane, Gunson, Bridget K., Criddle, David N., Pirmohamed, Munir, Grützmann, Robert, Michl, Patrick, Greenhalf, William, Molven, Anders, Sutton, Robert, Rosendahl, Jonas
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5089759/
https://ncbi.nlm.nih.gov/pubmed/27802312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165567
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires