The mucinous domain of pancreatic carboxyl-ester lipase (CEL) contains core 1/core 2 O-glycans that can be modified by ABO blood group determinants

Carboxyl-ester lipase (CEL) is a pancreatic fat-digesting enzyme associated with human disease. Rare mutations in the CEL gene cause a syndrome of pancreatic exocrine and endocrine dysfunction denoted MODY8, whereas a recombined CEL allele increases the risk for chronic pancreatitis. Moreover, CEL h...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: El Jellas, Khadija, Johansson, Bente B., Fjeld, Karianne, Antonopoulos, Aristotelis, Immervoll, Heike, Choi, Man H., Hoem, Dag, Lowe, Mark E., Lombardo, Dominique, Njølstad, Pål R., Dell, Anne, Mas, Eric, Haslam, Stuart M., Molven, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302156/
https://ncbi.nlm.nih.gov/pubmed/30315106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.001934
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