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NLRP12 Modulates Host Defense through IL-17A-CXCL1 Axis
We used an extracellular pathogen Klebsiella pneumoniae to determine the role of NLRP12 since this bacterium is associated with devastating pulmonary infections. We found human myeloid cells (neutrophils and macrophages) and non-myeloid cells (epithelial cells) show upregulation of NLRP12 in human p...
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| 發表在: | Mucosal Immunol |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5089371/ https://ncbi.nlm.nih.gov/pubmed/26349659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2015.80 |
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