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Both TRIF-Dependent and MyD88-dependent Signaling Contributes to Host Defense Against Pulmonary Klebsiella infection

Klebsiella pneumoniae (Kp) causes extensive lung damage. Toll-like receptor (TLR) signaling involves adaptors TRIF and MyD88. However, the relative contribution of TRIF and MyD88 signaling in host defense against pulmonary Kp infection have not been elucidated. Therefore, we investigated the role of...

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Bibliographische Detailangaben
Hauptverfasser: Cai, Shanshan, Batra, Sanjay, Shen, Li, Wakamatsu, Nobuko, Jeyaseelan, Samithamby
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777750/
https://ncbi.nlm.nih.gov/pubmed/19846873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901033
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