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Both TRIF-Dependent and MyD88-dependent Signaling Contributes to Host Defense Against Pulmonary Klebsiella infection

Klebsiella pneumoniae (Kp) causes extensive lung damage. Toll-like receptor (TLR) signaling involves adaptors TRIF and MyD88. However, the relative contribution of TRIF and MyD88 signaling in host defense against pulmonary Kp infection have not been elucidated. Therefore, we investigated the role of...

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Detalhes bibliográficos
Main Authors: Cai, Shanshan, Batra, Sanjay, Shen, Li, Wakamatsu, Nobuko, Jeyaseelan, Samithamby
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777750/
https://ncbi.nlm.nih.gov/pubmed/19846873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901033
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