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Both TRIF-Dependent and MyD88-dependent Signaling Contributes to Host Defense Against Pulmonary Klebsiella infection

Klebsiella pneumoniae (Kp) causes extensive lung damage. Toll-like receptor (TLR) signaling involves adaptors TRIF and MyD88. However, the relative contribution of TRIF and MyD88 signaling in host defense against pulmonary Kp infection have not been elucidated. Therefore, we investigated the role of...

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Détails bibliographiques
Auteurs principaux: Cai, Shanshan, Batra, Sanjay, Shen, Li, Wakamatsu, Nobuko, Jeyaseelan, Samithamby
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777750/
https://ncbi.nlm.nih.gov/pubmed/19846873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901033
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