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IFN-γ Induction by Neutrophil-derived IL-17A Homodimer Augments Pulmonary Antibacterial Defense

The role of IL-17A in host defense against Legionella pneumophila remains elusive. To address this issue, we used Il17a(−/−), Il17f(−/−), and Il17a/Il17f(−/−) mice on a C57Bl/6 (non-permissive) background and IL-17 neutralizing Abs in mice on an A/J (permissive) background. Higher bacterial (L.pneum...

詳細記述

保存先:
書誌詳細
出版年:Mucosal Immunol
主要な著者: Cai, Shanshan, Batra, Sanjay, Langohr, Ingeborg, Iwakura, Yochiro, Jeyaseelan, Samithamby
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785101/
https://ncbi.nlm.nih.gov/pubmed/26349661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2015.95
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