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NLRP12 Modulates Host Defense through IL-17A-CXCL1 Axis

We used an extracellular pathogen Klebsiella pneumoniae to determine the role of NLRP12 since this bacterium is associated with devastating pulmonary infections. We found human myeloid cells (neutrophils and macrophages) and non-myeloid cells (epithelial cells) show upregulation of NLRP12 in human p...

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Detalhes bibliográficos
Publicado no:Mucosal Immunol
Main Authors: Cai, Shanshan, Batra, Sanjay, Piero, Fabio Del, Jeyaseelan, Samithamby
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5089371/
https://ncbi.nlm.nih.gov/pubmed/26349659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2015.80
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