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The Role of DNA Methylation in the Metabolic Memory Phenomenon Associated With the Continued Progression of Diabetic Retinopathy

PURPOSE: Clinical and experimental studies have shown that diabetic retinopathy progression does not halt after termination of hyperglycemia, suggesting a “metabolic memory” phenomenon. DNA is highly dynamic, and cytosine methylation changes can last for several years. In diabetes, DNA methylation r...

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Vydáno v:Invest Ophthalmol Vis Sci
Hlavní autoři: Mishra, Manish, Kowluru, Renu A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Association for Research in Vision and Ophthalmology 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5089211/
https://ncbi.nlm.nih.gov/pubmed/27787562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-19759
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