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Epigenetic Modification of Mitochondrial DNA in the Development of Diabetic Retinopathy

PURPOSE: Retinal mitochondria are dysfunctional in diabetes, and mitochondrial DNA (mtDNA) is damaged and its transcription is compromised. Our aim was to investigate the role of mtDNA methylation in the development of diabetic retinopathy. METHODS: Effect of high glucose (20 mM) on mtDNA methylatio...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Invest Ophthalmol Vis Sci
मुख्य लेखकों: Mishra, Manish, Kowluru, Renu A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Association for Research in Vision and Ophthalmology 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525675/
https://ncbi.nlm.nih.gov/pubmed/26241401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-16937
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