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Epigenetic Modification of Mitochondrial DNA in the Development of Diabetic Retinopathy
PURPOSE: Retinal mitochondria are dysfunctional in diabetes, and mitochondrial DNA (mtDNA) is damaged and its transcription is compromised. Our aim was to investigate the role of mtDNA methylation in the development of diabetic retinopathy. METHODS: Effect of high glucose (20 mM) on mtDNA methylatio...
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| 出版年: | Invest Ophthalmol Vis Sci |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Association for Research in Vision and Ophthalmology
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4525675/ https://ncbi.nlm.nih.gov/pubmed/26241401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-16937 |
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