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Highly restricted human T cell repertoire in peripheral blood and tissue-infiltrating lymphocytes in Omenn's syndrome.

Omenn's syndrome is an inherited human combined immunodeficiency condition characterized by the presence of a large population of activated and tissue-infiltrating T cells. Analysis of the TCRB repertoire revealed a highly restricted TCRBV usage in three patients. More strikingly, T cell clones...

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Autori principali: Rieux-Laucat, F, Bahadoran, P, Brousse, N, Selz, F, Fischer, A, Le Deist, F, De Villartay, J P
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC508889/
https://ncbi.nlm.nih.gov/pubmed/9664072
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