Analysis of T cell receptor repertoire of muscle-infiltrating T lymphocytes in polymyositis. Restricted V alpha/beta rearrangements may indicate antigen-driven selection.

Polymyositis is an inflammatory myopathy characterized by mononuclear cell infiltration of muscle tissue. Myocytotoxic T lymphocytes have been recognized in the infiltrates, but the muscle antigen, target of the immune attack, has not been identified. Molecular characterization of the variable regio...

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Bibliografiske detaljer
Main Authors: Mantegazza, R, Andreetta, F, Bernasconi, P, Baggi, F, Oksenberg, J R, Simoncini, O, Mora, M, Cornelio, F, Steinman, L
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC443358/
https://ncbi.nlm.nih.gov/pubmed/8514895
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