Highly restricted human T cell repertoire in peripheral blood and tissue-infiltrating lymphocytes in Omenn's syndrome.

Omenn's syndrome is an inherited human combined immunodeficiency condition characterized by the presence of a large population of activated and tissue-infiltrating T cells. Analysis of the TCRB repertoire revealed a highly restricted TCRBV usage in three patients. More strikingly, T cell clones...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Rieux-Laucat, F, Bahadoran, P, Brousse, N, Selz, F, Fischer, A, Le Deist, F, De Villartay, J P
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 1998
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508889/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9664072/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI332
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