Halting of Caspase Activity Protects Tau from MC1-Conformational Change and Aggregation

Intracellular neurofibrillary tangles (NFTs) are the hallmark of Alzheimer’s disease and other tauopathies in which tau, a microtubule-associated protein, loses its ability to stabilize microtubules. Several post-translational modifications including phosphorylation and truncation increase tau’s pro...

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Dades bibliogràfiques
Publicat a:J Alzheimers Dis
Autors principals: Mead, Emma, Kestoras, Dimitra, Gibson, Yolanda, Hamilton, Lucy, Goodson, Ross, Jones, Sophie, Eversden, Sarah, Davies, Peter, O’Neill, Michael, Hutton, Michael, Szekeres, Philip, Wolak, Joanna
Format: Artigo
Idioma:Inglês
Publicat: IOS Press 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5088409/
https://ncbi.nlm.nih.gov/pubmed/27589517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-150960
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