KDM2B recruitment of the Polycomb group complex, PRC1.1, requires cooperation between PCGF1 and BCORL1

KDM2B recruits H2A-ubiquitinating activity of a non-canonical Polycomb Repression Complex 1 (PRC1.1) to CpG islands, facilitating gene repression. We investigated the molecular basis of recruitment using in vitro assembly assays to identify minimal components, subcomplexes and domains required for r...

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Gepubliceerd in:Structure
Hoofdauteurs: Wong, Sarah J., Gearhart, Micah D., Taylor, Alexander B., Nanyes, David R., Ha, Daniel J., Robinson, Angela K., Artigas, Jason A., Lee, Oliver J., Demeler, Borries, Hart, P. John, Bardwell, Vivian J., Kim, Chongwoo A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5088048/
https://ncbi.nlm.nih.gov/pubmed/27568929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2016.07.011
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