Structure of the Polycomb Group protein PCGF1 (NSPC1) in complex with BCOR reveals basis for binding selectivity of PCGF homologs

Polycomb Group RING finger homologs (PCGF1, 2, 3, 4, 5 and 6) are critical components in the assembly of distinct Polycomb Repression Complex 1 (PRC1) related complexes. Here we identify a protein interaction domain in BCL6 co-repressor, BCOR, which binds the ubiquitin-like RAWUL domain of PCGF1 (NS...

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Main Authors: Junco, Sarah E., Wang, Renjing, Gaipa, John C., Taylor, Alexander B., Schirf, Virgil, Gearhart, Micah D., Bardwell, Vivian J., Demeler, Borries, Hart, P. John, Kim, Chongwoo A.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003909/
https://ncbi.nlm.nih.gov/pubmed/23523425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.02.013
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