DNA Methylation of PITX2 and PANCR Is Prognostic for Overall Survival in Patients with Resected Adenocarcinomas of the Biliary Tract

Biliary tract cancers (BTC) are rare but highly aggressive malignant epithelial tumors. In order to improve the outcome in this lethal disease, novel biomarkers for diagnosis, prognosis, and therapy response prediction are urgently needed. DNA promoter methylation of PITX2 variants (PITX2ab, PITX2c)...

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Publicat a:PLoS One
Autors principals: Uhl, Barbara, Dietrich, Dimo, Branchi, Vittorio, Semaan, Alexander, Schaefer, Pauline, Gevensleben, Heidrun, Rostamzadeh, Babak, Lingohr, Philipp, Schäfer, Nico, Kalff, Jörg C., Kristiansen, Glen, Matthaei, Hanno
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087948/
https://ncbi.nlm.nih.gov/pubmed/27798672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165769
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