DNA Methylation of PITX2 and PANCR Is Prognostic for Overall Survival in Patients with Resected Adenocarcinomas of the Biliary Tract

Biliary tract cancers (BTC) are rare but highly aggressive malignant epithelial tumors. In order to improve the outcome in this lethal disease, novel biomarkers for diagnosis, prognosis, and therapy response prediction are urgently needed. DNA promoter methylation of PITX2 variants (PITX2ab, PITX2c)...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Uhl, Barbara, Dietrich, Dimo, Branchi, Vittorio, Semaan, Alexander, Schaefer, Pauline, Gevensleben, Heidrun, Rostamzadeh, Babak, Lingohr, Philipp, Schäfer, Nico, Kalff, Jörg C., Kristiansen, Glen, Matthaei, Hanno
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087948/
https://ncbi.nlm.nih.gov/pubmed/27798672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165769
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