DNA Methylation of PITX2 and PANCR Is Prognostic for Overall Survival in Patients with Resected Adenocarcinomas of the Biliary Tract

Biliary tract cancers (BTC) are rare but highly aggressive malignant epithelial tumors. In order to improve the outcome in this lethal disease, novel biomarkers for diagnosis, prognosis, and therapy response prediction are urgently needed. DNA promoter methylation of PITX2 variants (PITX2ab, PITX2c)...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Uhl, Barbara, Dietrich, Dimo, Branchi, Vittorio, Semaan, Alexander, Schaefer, Pauline, Gevensleben, Heidrun, Rostamzadeh, Babak, Lingohr, Philipp, Schäfer, Nico, Kalff, Jörg C., Kristiansen, Glen, Matthaei, Hanno
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087948/
https://ncbi.nlm.nih.gov/pubmed/27798672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165769
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