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Natural killer cell recognition of in vivo drug-induced senescent multiple myeloma cells

Recognition of tumor cells by the immune system is a key step in cancer eradication. Melphalan is an alkylating agent routinely used in the treatment of patients with multiple myeloma (MM), but at therapeutic doses it leads to an immunosuppressive state due to lymphopenia. Here, we used a mouse mode...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Antonangeli, Fabrizio, Soriani, Alessandra, Ricci, Biancamaria, Ponzetta, Andrea, Benigni, Giorgia, Morrone, Stefania, Bernardini, Giovanni, Santoni, Angela
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087311/
https://ncbi.nlm.nih.gov/pubmed/27853638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1218105
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