Natural killer cell recognition of in vivo drug-induced senescent multiple myeloma cells

Recognition of tumor cells by the immune system is a key step in cancer eradication. Melphalan is an alkylating agent routinely used in the treatment of patients with multiple myeloma (MM), but at therapeutic doses it leads to an immunosuppressive state due to lymphopenia. Here, we used a mouse mode...

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Publicado en:Oncoimmunology
Main Authors: Antonangeli, Fabrizio, Soriani, Alessandra, Ricci, Biancamaria, Ponzetta, Andrea, Benigni, Giorgia, Morrone, Stefania, Bernardini, Giovanni, Santoni, Angela
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2016
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087311/
https://ncbi.nlm.nih.gov/pubmed/27853638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1218105
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