Natural killer cell recognition of in vivo drug-induced senescent multiple myeloma cells

Recognition of tumor cells by the immune system is a key step in cancer eradication. Melphalan is an alkylating agent routinely used in the treatment of patients with multiple myeloma (MM), but at therapeutic doses it leads to an immunosuppressive state due to lymphopenia. Here, we used a mouse mode...

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Publicat a:Oncoimmunology
Autors principals: Antonangeli, Fabrizio, Soriani, Alessandra, Ricci, Biancamaria, Ponzetta, Andrea, Benigni, Giorgia, Morrone, Stefania, Bernardini, Giovanni, Santoni, Angela
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2016
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Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087311/
https://ncbi.nlm.nih.gov/pubmed/27853638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1218105
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