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Small-molecule control of cytokine function: new opportunities for treating immune disorders

Manipulating cytokine function with protein-based drugs has proven effective for treating a wide variety of autoimmune and auto-inflammatory disorders. However, the limited ability of protein-based drugs to modulate intracellular targets, including many implicated by studies of the genetics and phys...

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Bibliographic Details
Published in:Curr Opin Chem Biol
Main Authors: Sundberg, Thomas B., Xavier, Ramnik J., Schreiber, Stuart L., Shamji, Alykhan F.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087273/
https://ncbi.nlm.nih.gov/pubmed/25222143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2014.08.013
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