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Imaging G protein–coupled receptors while quantifying their ligand-binding free-energy landscape
Imaging native membrane receptors and testing how they interact with ligands is of fundamental interest in the life sciences but has proven remarkably difficult to accomplish. Here, we introduce an approach that uses force-distance curve–based atomic force microscopy to simultaneously image single n...
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| Publicado no: | Nat Methods |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5087271/ https://ncbi.nlm.nih.gov/pubmed/26167642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3479 |
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