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Identifying and quantifying two ligand-binding sites while imaging native human membrane receptors by AFM

A current challenge in life sciences is to image cell membrane receptors while characterizing their specific interactions with various ligands. Addressing this issue has been hampered by the lack of suitable nanoscopic methods. Here we address this challenge and introduce multifunctional high-resolu...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Pfreundschuh, Moritz, Alsteens, David, Wieneke, Ralph, Zhang, Cheng, Coughlin, Shaun R., Tampé, Robert, Kobilka, Brian K., Müller, Daniel J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Pub. Group 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4660198/
https://ncbi.nlm.nih.gov/pubmed/26561004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9857
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