Paramagnetic Ligand Tagging To Identify Protein Binding Sites

[Image: see text] Transient biomolecular interactions are the cornerstones of the cellular machinery. The identification of the binding sites for low affinity molecular encounters is essential for the development of high affinity pharmaceuticals from weakly binding leads but is hindered by the lack...

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Publicat a:J Am Chem Soc
Autors principals: Brath, Ulrika, Swamy, Shashikala I., Veiga, Alberte X., Tung, Ching-Chieh, Van Petegem, Filip, Erdélyi, Máté
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2015
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583072/
https://ncbi.nlm.nih.gov/pubmed/26289584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b06220
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