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The impact of interchain hydrogen bonding on β‐hairpin stability is readily predicted by molecular dynamics simulation

Peptides are frequently used model systems for protein folding. They are also gaining increased importance as therapeutics. Here, the ability of molecular dynamics (MD) simulation for describing the structure and dynamics of β‐hairpin peptides was investigated, with special attention given to the im...

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Vydáno v:Biopolymers
Hlavní autoři: Niebling, Stephan, Danelius, Emma, Brath, Ulrika, Westenhoff, Sebastian, Erdélyi, Máté
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744756/
https://ncbi.nlm.nih.gov/pubmed/25968880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.22671
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