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Transferable model for chromosome architecture

In vivo, the human genome folds into a characteristic ensemble of 3D structures. The mechanism driving the folding process remains unknown. We report a theoretical model for chromatin (Minimal Chromatin Model) that explains the folding of interphase chromosomes and generates chromosome conformations...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Di Pierro, Michele, Zhang, Bin, Aiden, Erez Lieberman, Wolynes, Peter G., Onuchic, José N.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087044/
https://ncbi.nlm.nih.gov/pubmed/27688758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1613607113
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