G6PC2 Modulates the Effects of Dexamethasone on Fasting Blood Glucose and Glucose Tolerance

The glucose-6-phosphatase catalytic subunit 2 (G6PC2) gene encodes an islet-specific glucose-6-phosphatase catalytic subunit. G6PC2 forms a substrate cycle with glucokinase that determines the glucose sensitivity of insulin secretion. Consequently, deletion of G6pc2 lowers fasting blood glucose (FBG...

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Publicado en:Endocrinology
Main Authors: Boortz, Kayla A., Syring, Kristen E., Lee, Rebecca A., Dai, Chunhua, Oeser, James K., McGuinness, Owen P., Wang, Jen-Chywan, O'Brien, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado: Endocrine Society 2016
Assuntos:
Special Series: Endocrine Society Centennial Celebration
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5086534/
https://ncbi.nlm.nih.gov/pubmed/27653037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1678
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