Neutrophil-mediated changes in vascular permeability are inhibited by topical application of aspirin-triggered 15-epi-lipoxin A4 and novel lipoxin B4 stable analogues.

Neutrophil (PMN) activation is critical in inflammation and reperfusion injury, suggesting that PMN-directed therapies may be of clinical use. Here, leukotriene B4 (LTB4)-induced PMN influx in ear skin was equivalent between 5-lipoxygenase knockout and wild-type mice. To explore actions of lipoxin (...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Takano, T, Clish, C B, Gronert, K, Petasis, N, Serhan, C N
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 1998
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508630/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9466977/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI1578
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