Leukotriene B(4) receptor transgenic mice reveal novel protective roles for lipoxins and aspirin-triggered lipoxins in reperfusion

Polymorphonuclear neutrophil (PMN) activation is pivotal in acute inflammation and injury from reperfusion. To elucidate components controlling PMNs in vivo, we prepared novel transgenic mice with the human leukotriene (LT) B(4) receptor (BLTR) for functional characterization. Overexpression of BLTR...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Chiang, Nan, Gronert, Karsten, Clish, Clary B., O’Brien, Jennifer A., Freeman, Mason W., Serhan, Charles N.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 1999
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC408424/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10430612/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI7016
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