Selectivity of Recombinant Human Leukotriene D(4), Leukotriene B(4), and Lipoxin A(4) Receptors with Aspirin-Triggered 15-epi-LXA(4) and Regulation of Vascular and Inflammatory Responses

Aspirin-triggered lipoxin A(4) (ATL, 15-epi-LXA(4)) and leukotriene D(4) (LTD(4)) possess opposing vascular actions mediated via receptors distinct from the LXA(4) receptor (ALX) that is involved in leukocyte trafficking. Here, we identified these receptors by nucleotide sequencing and demonstrate t...

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Main Authors: Gronert, Karsten, Martinsson-Niskanen, Titti, Ravasi, Saula, Chiang, Nan, Serhan, Charles N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2001
Assuntos:
Short Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850279/
https://ncbi.nlm.nih.gov/pubmed/11141472
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