Aspirin-triggered 15-Epi-Lipoxin A(4) (LXA(4)) and LXA(4) Stable Analogues Are Potent Inhibitors of Acute Inflammation: Evidence for Anti-inflammatory Receptors

Lipoxins are bioactive eicosanoids that are immunomodulators. In human myeloid cells, lipoxin (LX) A(4) actions are mediated by interaction with a G protein–coupled receptor. To explore functions of LXA(4) and aspirin-triggered 5(S),6(R),15(R)-trihydroxy-7,9,13-trans-11-cis–eicosatetraenoic acid (15...

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Hauptverfasser: Takano, Tomoko, Fiore, Stefano, Maddox, Jane F., Brady, Hugh R., Petasis, Nicos A., Serhan, Charles N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1997
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196289/
https://ncbi.nlm.nih.gov/pubmed/9151906
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