Activating transcription factor-4 promotes mineralization in vascular smooth muscle cells

Emerging evidence indicates that upregulation of the ER stress–induced pro-osteogenic transcription factor ATF4 plays an important role in vascular calcification, a common complication in patients with aging, diabetes, and chronic kidney disease (CKD). In this study, we demonstrated the pathophysiol...

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Bibliografiska uppgifter
I publikationen:JCI Insight
Huvudupphovsmän: Masuda, Masashi, Miyazaki-Anzai, Shinobu, Keenan, Audrey L., Shiozaki, Yuji, Okamura, Kayo, Chick, Wallace S., Williams, Kristina, Zhao, Xiaoyun, Rahman, Shaikh Mizanoor, Tintut, Yin, Adams, Christopher M., Miyazaki, Makoto
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2016
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085604/
https://ncbi.nlm.nih.gov/pubmed/27812542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.88646
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