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Activating transcription factor-4 promotes mineralization in vascular smooth muscle cells
Emerging evidence indicates that upregulation of the ER stress–induced pro-osteogenic transcription factor ATF4 plays an important role in vascular calcification, a common complication in patients with aging, diabetes, and chronic kidney disease (CKD). In this study, we demonstrated the pathophysiol...
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| Publicado no: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5085604/ https://ncbi.nlm.nih.gov/pubmed/27812542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.88646 |
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