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Regulated overexpression of interleukin 11 in the lung. Use to dissociate development-dependent and -independent phenotypes.

Standard overexpression transgenic approaches are limited in their ability to model waxing and waning diseases and frequently superimpose development-dependent and -independent phenotypic manifestations. We used the clara cell 10-kD protein (CC10) promoter and the reverse tetracycline transactivator...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autores principales: Ray, P, Tang, W, Wang, P, Homer, R, Kuhn, C, Flavell, R A, Elias, J A
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 1997
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508450/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9366564/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119792
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