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Mediation of interleukin-11-dependent biological responses by a soluble form of the interleukin-11 receptor.

Interleukin-11 (IL-11) is a polyfunctional cytokine whose biological actions require a specific IL-11 receptor (IL-11R) and the transmembrane transducer gp130. Here we report the production of a soluble form of the murine IL-11R and demonstrate that it interacts with IL-11 ligand with high affinity....

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Bibliografiska uppgifter
Huvudupphovsmän: Karow, J, Hudson, K R, Hall, M A, Vernallis, A B, Taylor, J A, Gossler, A, Heath, J K
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1996
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217647/
https://ncbi.nlm.nih.gov/pubmed/8809037
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