Leptin- or troglitazone-induced lipopenia protects islets from interleukin 1beta cytotoxicity.

Interleukin 1beta (IL-1beta)-induced beta cell cytotoxicity has been implicated in the autoimmune cytotoxicity of insulin-dependent diabetes mellitus. These cytotoxic effects may be mediated by nitric oxide (NO). Since long-chain fatty acids (FFA), like IL-1beta, upregulate inducible nitric oxide sy...

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Detaylı Bibliyografya
Asıl Yazarlar: Shimabukuro, M, Koyama, K, Lee, Y, Unger, R H
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1997
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC508358/
https://ncbi.nlm.nih.gov/pubmed/9312173
Etiketler: Etiketle
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