Heterologous introns can enhance expression of transgenes in mice.
In a previous study we showed that genomic constructs were expressed more efficiently in transgenic mice than constructs that were identical except for the lack of introns. Using the mouse metallothionein promoter-rat growth hormone gene construct as a model, we show that the first intron of the rat...
Na minha lista:
| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1991
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50834/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1988947/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.2.478 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|