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Expression of a mutated bovine growth hormone gene suppresses growth of transgenic mice.

To determine the importance of the third alpha-helix in bovine growth hormone (bGH) relative to growth-related biological activities, the following experimental approach was used: (i) mutagenesis of helix III of bGH to generate an idealized amphiphilic helix; (ii) in vitro expression analyses of the...

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Dettagli Bibliografici
Autori principali: Chen, W Y, Wight, D C, Wagner, T E, Kopchick, J J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1990
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC54261/
https://ncbi.nlm.nih.gov/pubmed/2367524
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